The film begins with the members of Janie and the Studs featuring Peter making their way to the front of Degrassi Community School as the last minutes of the school year tick down. Knowing that Spinner and Jane want to spend more time together in the summer, Spinner hires Emma as a new server, giving her instructions not to use the sandwich grill until she is fully oriented. With The Dot now employed, Spinner and Jane head to the Coyne's pool party. While in the dressing tent, Holly J. and Jane talk about the time Jane cheated on Spinner with Holly J.'s boyfriend, Declan, with Spinner listening outside. This new information, along with Jane leaving the country to go to college, causes Spinner to break-up with Jane in a big scene. Upon returning to The Dot, Spinner finds it on fire, as a result of Emma using the shorting sandwich grill. This causes Spinner to fall into an even deeper depression, where he violently removes all Jane memorabilia from his loft.
With nothing to do for the summer for Jane, she gets invited to live in the penthouse suite in Manhattan with Holly J., Declan and his sister Fiona. After being a third wheel to Declan and Holly J., Jane continues to explore New York, and gets invited to front an indie band, which will be playing on TVM, the music channel where Holly J. is about to start her internship. TVM is a parody of MTV, but was filmed in the MuchMusic studios in 299 Queen Street West, Toronto. On Holly J.'s first day, she runs into Jay Manuel, as himself, who gives her a warning about her new boss, Kristin, who is played by MTV Canada host Jessi Cruickshank. Holly J. also finds out that Fiona will be interning there, as a result of her jealousy to Holly J.'s time with Declan. A feud breaks out between Holly J. and Fiona, attempting to hurt each other emotionally. Holly J. locks Fiona in a room before a live broadcast, and Fiona attempts to get Declan on her side. She plans a party in their penthouse, to show Holly J., Declan's ex-girlfriends, but when this does not affect Holly J., she proceeds to kiss her brother Declan, to make a scene. This causes Declan to side with his seemingly crazy sister, and Holly J. running out for the night. The following morning, though, he talks to Holly J., winning her back, and asking Fiona to move out.
In an attempt to cheer up Spinner, Emma, Manny, and Jay "kidnap" him, and take him to a casino hotel at Niagara Falls. After some successful games of blackjack, Emma and Spinner become drunk, and wake up the following morning, not remembering what had happened. They find out that they spent their winnings on a legal marriage, and an ugly, un-returnable ring. In the following days they become closer to each other, and begin to think that they may not get a divorce. When Spinner tells Jane that they will hold a ceremony that Saturday, Jane realizes that she still has feelings for him, and convinces Holly J. and Declan to drive her back to Toronto. When Spinner and Emma start to question their marriage, they both say to each other that they want to wait to see if it works. They each go back to their friends, retelling the conversation in their head, until they realize that they do love each other. Spinner runs back to the Simpson/Nelson house to profess his love for Emma, as Snake and Spike have returned home from their vacation. And everyone decides to hold the wedding ceremony.
Not wanting Jane to stop the wedding, Holly J. and Declan try to slow down the road trip, until Jane steals the car. She reaches the lakeside party before the ceremony is about to begin, and finds Spinner's tent. After seeing that Spinner is in love with Emma, she allows the wedding to continue. The movie ends at the dance -after the wedding.
- As with Degrassi Takes Hollywood, the majority of this film was shot in Canada. Green-screen was utilized in order to get certain scenes done.
- This marks the last appearances of Manny, Jane, Danny, Jay, Spike, and Ms. Hatzilakos. This also marks the last regular appearances of Spinner, Emma, and Johnny.
- Emma and Spinner get married.
- This movie marks the end of Spinner and Jane's second and final relationship.
- Spinner makes a reference to Emma, Manny and Jay to the Season 8 Episode, Danger Zone, when he was taken hostage by a former Lakehurst student, Chris.
- Toby may have been at Emma and Spinner's wedding by standing behind Liberty. Though it is confirmed he was not there, if you look closely during the wedding, you can see a man who looks a bit similar to Toby.
- This was the first episode without a freeze frame at the end in the whole Degrassi series.
- This episode is the third to take place during Summer Vacation. The others were School's Out! and Mother and Child Reunion, and later Nowhere to Run and Summertime.
- The Dot exploded in this movie, and they had to make a new one.
- Second ever Degrassi Movie in the TNG series, the first being: Degrassi Goes Hollywood. However, it is the third movie in the Degrassi Franchise.
- Spinner makes a reference to Season 1 when he boycotted the cafeteria and, Season 2 when he got a boner in class.
- This movie had three names, "Degrassi Takes Manhattan", "The Heat Is On", and "The Rest Of My Life".
- This movie brought TeenNick its highest ratings ever, the most watched telecast on the network, and the most watched telecast by teens on the evening of 19 July 2010.
- Jessi Cruickshank, who plays Holly J.'s boss Kristin, is the second The After Show host to appear in a Degrassi movie. Her After Show co-host Dan Levy co-starred in Degrassi Goes Hollywood as Paige Michalchuk's boss Robbie, a film producer.
- In the United States, this is the first episode that is just called Degrassi, without the The Next Generation tagline.
- Although this episode aired 3 days before The Boiling Point started in Canada, and 1 day before it aired in The United States, it is considered the Season 9 finale.
- This marks the first time that Drake, who portrayed Jimmy Brooks, was mentioned. The second was in I Want It That Way (2), and the third was in #BootyCall.
Regular Cast (Ordered alphabetically)
- Raymond Ablack as Sav Bhandari
- Dalmar Abuzeid as Danny Van Zandt
- Charlotte Arnold as Holly J. Sinclair
- Paula Brancati as Jane Vaughn
- Stefan Brogren as Archie Simpson
- Annie Clark as Fiona Coyne
- Jahmil French as Dave Turner
- Jamie Johnston as Peter Stone
- Shane Kippel as Spinner Mason
- Landon Liboiron as Declan Coyne
- Jajube Mandiela as Chantay Black
- Miriam McDonald as Emma Nelson
- Scott Paterson as Johnny DiMarco
- Aislinn Paul as Clare Edwards
- Melinda Shankar as Alli Bhandari
- Cassie Steele as Manny Santos
- Jessica Tyler as Jenna Middleton
- Sarah Barrable-Tishauer as Liberty Van Zandt
- Melissa DiMarco as Daphne Hatzilakos
- Mike Lobel as Jay Hogart
- Amanda Stepto as Christine Nelson
- Jessi Cruickshank as Kristin
- Anna Cyzon as Siobhan
- Kenny Hotz as Ron
- Suresh John as Gamal
- Tyler Kyte as himself
- Elaine Lui as herself
- Jay Manuel as himself
- Forbes March as George
- Colin Mochrie as Larry
- Doug Morency as Mr. Bince
- Mary Murphy as Sales clerk
- Joy Tanner as Laura Coyne
- Sweet Thing as themselves
- Lizz Alexander as Tattoo artist
- Ian Blackwood as George's keyboardist
- Robin Craig as Mrs. Mason
- R.O. Glasgow as Dealer
- Elizabeth Lofranco as Intern 1
- Ian MacIntyre as Intern 2
- Sydney Van Delft as Chloe
- Rudy Webb as Doorman
- Jelena Zivanovic as Morgan
- Holly J.: "This is New York Holly J., bitch!"
- Holly J.: "I'm done coming second to your sister Declan!"
- Holly J.: "If anything's gross it's your jealousy, and frankly, it's inappropriate!"
Fiona: "You want inappropriate?"
- Declan (to Fiona): "You're messed up Fi, and this time I don't think I can help you."
- Spinner (to Jane): "I HEARD YOU!"
- Spinner (to Holly J.): "SHUT UP! You knew about this!"
- Spinner (to Emma): "What did we do last night?"
- Larry (to Emma): "Ever had a hernia? Not fun."
- Peter (to Spinner): "It's hammer time!"
- Spike (to Emma): "How pregnant are you?"
Emma: "Not even a little bit."
- Manny (to Jane): "You are not ruining my best friend's wedding!"
- Holly J. (to Declan): "I feel like I'm in the Princess Diaries!"
- Declan (to everyone): "I love New York."
- Fiona (to Holly J.): "Boyfriends are temporary. Brothers are forever."
- Spinner (to Emma): "You're like some card-playing Yoda! You know that? Except, way better looking."
- Record seller (to George): "Breakin' up's a bitch, bro."
- Jane (to Spinner): "You look happy..."
- Jane (to Holly J.): "Well, sometimes good things happen out of a break up!
- Jay (to Emma and Spinner): "Whoa, someones on a roll!"
- Manny (to Emma, Jay and Spinner): "I blame margaritas. You ready?"
- Spinner (to Emma): "Drama class boner."
- Fiona (to Declan): "I made some calls, no biggie.
- Holly J. (to Declan and Fiona): "Declan Coyne, speechless. I really had seen everything."
- Fiona (to Holly J., Morgan, Chloe and Blake): "My brother is just gaga about her."
- Emma (to Spinner): "Mhmm, smells yummy!"
- Declan (to Fiona): "Rough night, sis?"
- Larry (to Spinner and Emma): "Are you sure you're okay with checking divorced every time you enter a contest?"
- Danny: "Well, I'm not telling Spinner that Jane's here."
Sav: "Man, if I tell him he will break me."
Danny: "You're overreacting."
Sav: "Man, I'm like a twig!"
- "The Great Escape" by Janie and the Studs Feat. Peter Stone - Heard during the opening scene when Janie and the Studs perform.
- "Tattoo Parlour" by Tim Welch
- "Way Better Now" by Speedmarket Avenue
- "Land Of Giants" by Hooded Fang
- "Leaders Of The Misled" by The New Cities
- "When They Fight, They Fight" by Generationals
- "I Wanna Rock" by Jeffery Brothers Band
- "Find Another Girl" by The Midways
- "Got To Be" by Latch Key Kid
- "N.Y.M." by The Damn Automatics
- "Here Today" by Flashin' Midnight - Heard when Jane auditions for Flashin' Midnight.
- "Change Of Seasons" by Sweet Thing
- "Maybe Love" by Flashin' Midnight and Jane - Heard when Flashin' Midnight performs on TVM.
- "Derriere (Are You Ready)" by Hipjoint Feat. Lil' Raven
- "Put Me On Your Playlist" by Confection
- "Busker Walk" by Tim Welch
- "Fine Line" by Alanna Clarke - Heard when Declan goes to the studio to ask Holly J. for a second chance.
- "Your Love is My Drug" by Ke$ha - Heard when Fiona kisses Declan.
- "Away From Sunshine" by Automatic Eye
- "Good Life" by Michelle Featherstone - Heard when Spinner and Emma decide to stay married.
- "What Goes Around" by Domenica
- "Fly Away" by Honey Ryder - Heard when Spinner professes his love for Emma.
- "Can You Hear Me Boys" by Aloha From Hell
- "I Trust You" by The Studs and Manny - Heard during the wedding when Manny performs.
Just Can't Get Enough • Shoot to Thrill • Close to Me • You Be Illin' • Wanna Be Startin' Somethin' • Beat It (1) • Beat It (2) • Waiting for a Girl Like You • Somebody • Heart Like Mine (1) • Heart Like Mine (2) • Holiday Road • Start Me Up • Why Can't This Be Love (1) • Why Can't This Be Love (2) • Innocent When You Dream • In Your Eyes • Keep On Loving You • Degrassi Takes Manhattan