In Drive, Spinner Mason hoped that Louisa would be able to get them tickets to Kid Elrick's concert as he believed that she worked in the music industry. However, Marco told him that she was a piano teacher.
In It's Raining Men, Marco and Dylan Michalchuk went on their first date. At the restaurant where they were eating, Marco and Dylan ran into Marco's homophobic Italian parents who made the evening awkward.
Season 4In King of Pain, it is revealed that she works at a pharmacy. She is fully supportive of Marco running for class president, including helping to make posters and attending then his school assembly to hear Marco's speech. She notices something is bothering Marco, when he was upset over his break up with Dylan, and accepts him upon coming out to her. She is very proud of Marco when he wins the election, and is happy that he made up with Dylan. She continues to keep her son's sexuality a secret from her husband until Marco eventually comes out to his father in Tell It to My Heart.
In Tell It to My Heart, Louisa has still not told her husband that Marco is gay.