|Intimacy Level||Best Friend, Former Rivals|
|Friendship Started||Prior to The Experiment (DJH 103)|
Degrassi Junior High Season 1
In The Experiment, Melanie and Kathleen are thinking about drugs and decide to try some. They buy some "drugs" from Joey Jeremiah and believe they are high for hours, though it is revealed that Joey gave them vitamin pills. They get revenge by teaming up with some of Joey's other victims by stripping him naked and locking him in the broom closet.
Degrassi Junior High Season 3
In Food for Thought, Melanie discovers that Kathleen has an eating disorder after reading Kathleen's food diary. Kathleen gets mad at Melanie for reading her food diary and is in denial that she has a problem. But after Kathleen faints in the hallway, Melanie tells Ms. Avery about what's wrong with Kathleen. Kathleen gets mad at Melanie for telling Ms. Avery and says that she does't need any help.
In Making Whoopee, Melanie, who has a crush on Snake, wants to be paired up with him for the Open House committee. Kathleen, despite still being angry at Melanie, pairs them up together. However Alison is paired up with Snake as well. Both girls fight over for his attention. Later, Melanie overhears Amy Holmes and Allison Hunter gossiping about Melanie and saying that her crush on Snake is pathetic and she's just a little kid. However, Kathleen stands up for Melanie which surprises Amy and Alison. Melanie and Kathleen make up and Kathleen reveals that she's get help for her eating disorder.
Degrassi High Season 1
In A New Start, Melanie and Kathleen are being targeted by the older students and tied up to a pole with bras and panties put out on front of them.
In Dream On, the girls try to go to their lockers but Tabi won't let them and starts to bully them. While feeling depressed, Kathleen meets a boy named Scott who asks her to join the play and that cheers Kathleen up. She is able to stand up to Tabi and she and Melanie are finally about to get to their lockers. Kathleen reveals that Scott invited her to go to a game with him.
In Nobody's Perfect, Melanie notices of how controlling Scott is but Kathleen does not want to reveal that Scott is abusing her. In the end, she dumps Scott.
In Just Friends, Scott would try to talk to Kathleen but Melanie tells him that she's too busy to talk to him so that he would leave her alone.
Degrassi High Season 2
In The All Nighter, the girls throw a surprise birthday party for Diana. Everybody, expect for Catilin decides to get high when Kathleen brings marijuana. Melanie, while high, then accidentally reveals that how Kathleen had an eating disorder and that Scott beat her. This makes Kathleen upset and she runs off. Melanie tries to apologize but Kathleen still doesn't forgive her.
- They both decided to try drugs at some point.
- Melanie was the first one to find out that Kathleen had an eating disorder.
- Melanie also found out that Scott was abusing Kathleen.
- They're both good friends with Diana Economopoulos, Caitlin Ryan and Maya Goldberg.
- Kathleen had a conflict with Melanie's good friend, Caitlin.
- Their friendship is somewhat similar to the friendship of Degrassi Class of 2011 graduates Anya MacPherson and Holly J. Sinclair.
- They both graduated in the Class of 1993.
- They were both self-conscious about their bodies: Melanie was self-conscious about her breast size and Kathleen was self-conscious about her weight.
- Their first lines were said to each other. Melanie: ("You know what happens? Junior high is a lot different than I thought it would be.") Kathleen: ("Yeah, too much homework.")
- They both smoked marijuana in The All Nighter.
- They both made their first appearances in Season 1 of Degrassi Junior High: Kathleen in The Big Dance and Melanie in The Experiment.
- They were both members of the Grade 7 class 7C from 1987 to 1988, the Grade 8 class 8A from 1988 to 1989 and the Grade 9 class 9A from 1989 to 1990.